The Brutal Combo is a powerful melee attack featured in Drake's Fortune. The Brutal Combo is started by pressing when you are close enough to an enemy. After the first punch has landed, press to continue the combo. After the second blow has landed, press again to finish the combo. Enemies killed with a Brutal Combo will drop more ammo. A Brutal Combo can't kill the Descendants. Drake uses a Brutal Combo to finish off Atoq Navarro at the end of Showdown.
|Kill five enemies with a brutal combo.|
|Kill twenty enemies with a brutal combo.|
|Kill five enemies in a row with a brutal combo.|
Killing five enemies with a brutal combo will unlock the medal, worth 10 points, and bronze trophy Brutal Brawler. Killing twenty will unlock a silver trophy and medal worth 30 points, called Brutal Slugger. Lastly the silver trophy Brutal Expert, worth 40 medal points, is unlocked upon killing five enemies in a row with the brutal combo. The easiest point for this challenge is at the start of the game, during the Ambushed, due to the relative weakness of the enemies fought.