Cartagena, Colombia is a location in Uncharted 3: Drake's Deception that appears in Chapter 2 - Greatness from Small Beginnings and Chapter 3 - Second-Story Work
Events in Uncharted 3
As a teenager, Nathan Drake came to Cartagena in order to steal Sir Francis Drake's ring from the Museo Marítimo. While there, he met Victor Sullivan and Katherine Marlowe who were also after the ring.
Appears In
Chapter 2 - Greatness from Small Beginnings
Chapter 3 - Second-Story Work
Chapter 21 - The Atlantis of the Sands