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The Museum of Natural History in New York appears in Uncharted: The Fourth Labyrinth.

Chapter 3[]

Nathan Drake, Victor Sullivan and Jada Hzujak go to the museum to meet Dr P. Cheney whilst investigating the death of Jada's father. Upon arrival, they are shown to the doctor's office by a college student, Gretchen, but they only discover that Cheney is dead. Nate and Jada begin to pursue the attacker through the museum, but are unable to keep up. The trio are forced to leave the museum after the police arrive.